DETERMINING THE NECESSITY OF COMPLEMENTARY AXILLARY DISSECTION IN BREAST CANCER PATIENTS WITH POSITIVE SENTINEL LYMPH NODE BY WAY OF ASSESSING NOMOGRAM METHODS

Autor: Dursun Burak ÖZDEMİR, Betül BOZKURT
Rok vydání: 2022
Předmět:
Zdroj: Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi. 54:405-411
ISSN: 1304-6187
Popis: AIM: Our aim was to evaluate the efficacies of different nomogram approaches, including the Memorial Sloan Kettering Cancer Centre (MSKCC), Stanford University, Tenon Hospital, Cambridge University and TR methods, in patients operated for breast cancer. MATERIAL AND METHOD: The study included 60 breast cancer patients who were operated on for breast cancer at Ankara Numune Training and Research Hospital, A2 General Surgery Clinic, between 2007 and 2012. All patients were sentinel lymph node (SLN)-positive and had undergone axillary lymph node dissection (ALND). Five different scoring systems were applied retrospectively to these 60 patients. Receiver operating characteristics (ROC) curves were created for the nomograms and the area under the curve (AUC) sensitivity and specificity results were calculated. RESULTS: Twenty-two patients (37%) had axillary non-SLN metastases. AUC values of MSKCC, Stanford, Cambridge, Tenon and TR nomogram were calculated as 0.646, 0.644, 0.62, 0.595, and 0.66, respectively. A significant difference was found between the groups with and without non-SLN metastasis in terms of SLN metastasis size (p = 0.013). CONCLUSION: The MSKCC, Stanford, Cambridge, Tenon, and TR nomogram models were found to have insufficient power to discriminate between patients with and without non-SLN metastases in patients with SLN-positive breast cancer (AUC values
Databáze: OpenAIRE