New Double-Chain and Aromatic (α-Hydroxyalkyl)phosphorus Amphiphiles

Autor:	Guita Etemad-Moghadam, Alice Brun
Rok vydání:	2002
Předmět:	Addition reaction Aqueous solution Hypophosphorous acid Phosphorus Organic Chemistry chemistry.chemical_element Ether Cleavage (embryo) Medicinal chemistry Catalysis chemistry.chemical_compound chemistry Phosphinic Acids Amphiphile Organic chemistry
Zdroj:	Synthesis. :1385-1390
ISSN:	1437-210X 0039-7881
Popis:	New double-chain bis-(α-hydroxyalkyl)phosphinic acids 1 are synthesized from NaH 2 PO 2 .H 2 O and aliphatic aldehydes. Direct and quantitative one-pot synthesis of new 4-alkoxybenzaldehydes 2 is realized from 1-bromoalkanesand 4-hydroxybenzaldehyde. Addition of NaH 2 PO 2 .H 2 O to aldehydes 2 leads to the formation of the bis-adducts and also to the cleavage of the ether bond. New [α-hydroxy-(4-alkoxybenzyl)]phosphinic acids 3 are prepared by addition of aldehydes 2 to aqueous hypophosphorous acid.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9551d48e0da43db1dd21795c77591f78 https://doi.org/10.1055/s-2002-33111 Zobrazit plný text záznamu