Development of the Process of p-Nitroacetophenone and Benzoic Acid Manufacture by the Liquid-Phase Oxidation of Aromatic Compounds

Autor:	Tatiana V. Bukharkina, Nikolai G. Digurov, and Sergey B. Mil'ko, Anna B. Shelud'ko
Rok vydání:	1999
Předmět:	chemistry.chemical_compound Chemistry Scientific method Diffusion Organic Chemistry P-nitroacetophenone Organic chemistry Liquid phase Physical and Theoretical Chemistry Aeration Benzene Acetophenone Benzoic acid
Zdroj:	Organic Process Research & Development. 3:404-408
ISSN:	1520-586X 1083-6160
DOI:	10.1021/op990030q
Popis:	The kinetic model of the ethyl benzene oxidation was applied to the design of the large-scale reactors of p-nitroacetophenone (chloramphenicol key intermediate) synthesis by p-nitroethyl benzene oxidation and benzoic acid synthesis by acetophenone oxidation. The factors allowing simplification of the above model are discussed. The height of the frothy (aerated) liquid layer in the oxidation tower securing the explosion-proof reaction conditions of acetophenone and p-nitroethyl benzene oxidation both in the kinetic and diffusion fields was calculated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::95463e6312a2d1ce5e07a1790ebee1ee https://doi.org/10.1021/op990030q Zobrazit plný text záznamu