Zinc Based Materials as Efficient Catalysts for a Clean Synthesis of Biginelli Product

Autor:	C. Rabia, M. Halouane, T. Mazari, C. Khiar, S. Menad, L. Bennini
Rok vydání:	2018
Předmět:	Green chemistry Solvent Reaction conditions chemistry Scientific method Product (mathematics) Biginelli reaction Organic chemistry chemistry.chemical_element Zinc Catalysis
Zdroj:	Proceedings of the Third International Symposium on Materials and Sustainable Development ISBN: 9783319897066
DOI:	10.1007/978-3-319-89707-3_39
Popis:	Ethyl6-methyl-2-oxo-4-phenyl-1,2,3,4 tetrahydropyrimidine-5-carboxylate, Bigenilli product (noted DHPMs) was synthesized in the presence of chlorides and nitrates of metals as catalysts, in mild free solvent conditions. High DHPM yields were obtained with Zn(NO3)2 (97%), ZnCl2 (90%) and CuCl2 (76%). The reaction heptagram inspired by the principles of green chemistry show that in our reaction conditions, Biginelli process complies with the principles of sustainable development.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9539672630031bcd008afe178c8e6868 https://doi.org/10.1007/978-3-319-89707-3_39 Zobrazit plný text záznamu