Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Itsin vitroRelease Studies

Autor: Konduru Mohana Raju, Vanarchi Rajineekanth, Antoine F. Mulaba-Bafubiandi, S. Ravindra, Kokkarachedu Varaprasad
Rok vydání: 2012
Předmět:
Zdroj: Polymer-Plastics Technology and Engineering. 51:1355-1360
ISSN: 1525-6111
0360-2559
Popis: In present investigation, a series of hydrogels, composed with Surfactant and poly(Acrylamide-co-Potassium acrylate), using Ammonium per sulfate(APS)/N,N,N 1 , N 1 -tetram ethylethylene diamine (TMEDA) initiating system and N,N 1-methylenebisacrlyamide (MBA) as crosslinker. The prepared hydrogel was characterized by using Fourier transform infrared spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Scanning electron microscopy (SEM). The controlled release characteristics of the matrices for Triprolidene hydrochloride (TH) were investigated in pH 7.4 media. Drug was released in a controlled manner up to 1400 min.
Databáze: OpenAIRE