Rh factor and Autonomic Function Test in Normal and Deep Breathing

Autor: Uppangala Chaitra, Rekha D Kini, Nayanatara Arunkumar, Sneha B Shetty, Bhagyalakshmi K, Vinodini N.A, Anupama N
Rok vydání: 2019
Předmět:
Zdroj: Indian Journal of Public Health Research & Development. 10:103
ISSN: 0976-5506
0976-0245
Popis: Background and Aim Studies have revealed a relationship between erythrocytic antigens of the ABO and Rh blood systems and cardiovascular pathology. Reduced heart rate variability (HRV) indicates an increased risk factor for the development of cardiovascular diseases. The present study was aimed to do correlative analysis of Rh blood groups and HRV in normal individuals. Materials and Method This cross sectional study includes 120 healthy medical students (18–22 years) of both sexes, from Kasturba Medical College, Mangalore, The study was approved by institutional ethical committee and study was carried out with written informed consent of students. All the subjects were grouped in to Rh positive blood group and Rh negative blood groups based on the result of standard slide haem agglutination technique. ECG of all the subjects was recorded in lead II for a period of five minutes and HRV was analysed by measuring the R-R intervals using a software “HRV soft 1.1 Version” software package. The HRV was analyzed both by the time domain method and frequency domain analysis during normal breathing. HRV is also analysed by deep breathing test for one minute and analyzed by the time domain method. In the time domain method, RMSSD-the square root of the mean squared differences of successive RR intervals (in milliseconds) SDNN-Standard deviation of RR intervals (in milliseconds), pNN50- percentage of differences between adjacent normal RR intervals exceeding 50 milliseconds were analyzed. In frequency domain method LF nu-Low frequency in normalized units, HF nuHigh frequency in normalized units, LF/HF-Ratio between low frequency and high frequency was measured. Statistical tests included in this study were ANOVA and student's unpaired ttest. P-value was taken as statistically significant at 5 percent confidence level (P
Databáze: OpenAIRE