Prevalence of COVID-19 in Egyptian Children With Hemoglobinopathies and Inherited Anemias
| Autor: | Ahlam M. Ismail, Suzan O Mousa, Nagwa Mohamed Sabry Mahmoud, Eman R Ghazawy |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty medicine.diagnostic_test Coronavirus disease 2019 (COVID-19) business.industry medicine.medical_treatment Splenectomy Complete blood count Computed tomography Hematology World health Oncology Pediatrics Perinatology and Child Health medicine Evaluated data Serum iron business Serum ferritin |
| Zdroj: | Journal of Pediatric Hematology/Oncology. 44:e954-e959 |
| ISSN: | 1077-4114 |
| DOI: | 10.1097/mph.0000000000002298 |
| Popis: | Since the World Health Organization (WHO) announced coronavirus disease-2019 (COVID-19) to be a pandemic, children's COVID-19 cases were generally less severe than adults. The aim of the study was to determine the prevalence of COVID-19 cases among children with hemoglobinopathies and other inherited anemias living in El-Minya Governorate, Egypt, who are at high risk of exposure to infection. This cross-sectional study evaluated data from 258 children with hemoglobinopathies and inherited anemias. A questionnaire was used to collect data about COVID-19 symptoms coupled with appropriate investigations (complete blood count, d-dimer, anti-COVID antibodies, chest computed tomography scans, and polymerase chain reaction). We found 38 of 258 (14.7%) children had mild to moderate COVID-19, while there were no cases with severe form of COVID-19. COVID-19 cases were significantly older (8.63±3.37 vs. 6.71±3.56 y, P=0.01), noncompliant to iron chelators (63.2% vs. 11.8%, P=0.01), had higher serum ferritin (2639.47±835.06 vs. 1038.95±629.87 ng/mL, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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