Abnormal cerebellum density in victims of rape with post-traumatic stress disorder: Voxel-based analysis of magnetic resonance imaging investigation

Autor: Ming-Xiang Wu, Lingjiang Li, Lian Duan, Xu-Chu Weng, Baoci Shan, Shuang-Ge Sui, Jian-Min Xu, Yan Zhang
Rok vydání: 2010
Předmět:
Zdroj: Asia-Pacific Psychiatry. 2:129-135
ISSN: 1758-5864
Popis: Introduction: Based on early studies of non-motor function in the cerebellum and dysfunction in the cerebellum of post-traumatic stress disorder ( PTSD) patients, we presumed that the cerebellum was involved in the neuropathology of cognitive and emotional processing of PTSD patients, while the density of some sub-areas of the cerebellum of PTSD patients was most likely abnormal. Methods: Eleven female victims of rape with PTSD and 12 age-matched female normal controls received 1.5 T 3D magnetic resonance imaging (MRI) scan. The scans were then analyzed using the voxel-based morphometry 2 ( VBM2) toolbox. Results: Victims of rape with PTSD showed increased cerebellum density on the left side compared with normal controls (P
Databáze: OpenAIRE