Superior anti-infective potential of eugenol–casein nanoparticles combined with polyethylene glycol against Colletotrichum musae infections
| Autor: | Peng Jin, Qizhen Du, Yahui Zhang, Xueyan Hao, Dingkui Qin, Shuya Han |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
biology
General Chemical Engineering Cold storage Nanoparticle 04 agricultural and veterinary sciences 02 engineering and technology General Chemistry Polyethylene glycol Colletotrichum musae 021001 nanoscience & nanotechnology biology.organism_classification 040401 food science Hydrophobe Eugenol chemistry.chemical_compound 0404 agricultural biotechnology chemistry Casein PEG ratio 0210 nano-technology Nuclear chemistry |
| Zdroj: | RSC Advances. 11:4646-4653 |
| ISSN: | 2046-2069 |
| Popis: | The aim of this study was to improve the stability of eugenol–casein nanoparticles (EL–CS-NPs) through polyethylene glycol (PEG) modification. The results show that modifying the EL–CS-NPs with PEG after loading with eugenol (EL) gives PEG–EL–CS-NPs, with increased stability. The NPs modified with higher-molecular-weight PEG showed better stability. A CS/PEG ratio of 200 : 1 (w/w) yielded the NPs with the best stability. A PEG20 K–EL–CS-NP dispersion remained stable in cold storage for over one year, and also exhibited stronger inhibitory effects against Colletotrichum musae inoculated on bananas than an EL–CS-NP dispersion, since it showed more prolonged sustained release of EL than the EL–CS-NP dispersion. Lyophilized PEG20 K–EL–CS-NP powder showed better effectiveness against mold on bread than lyophilized EL–CS-NPs powder. Using PEG to modify CS-NPs shows potential for improving the stability of CS-NPs loaded with hydrophobic substances for delivery in the fields of food and agriculture. |
| Databáze: | OpenAIRE |
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