Ifosfamide is an active drug for chemotherapy of metastatic cystosarcoma phyllodes
| Autor: | J. Alan McKinna, John B. Sckofield, Robert E. Hawkins, Eve Wiltskaw, Cyril Fisher |
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| Rok vydání: | 1992 |
| Předmět: |
Drug
Cancer Research Chemotherapy medicine.medical_specialty Ifosfamide business.industry medicine.medical_treatment media_common.quotation_subject Mammary gland Disease medicine.disease Surgery Metastasis medicine.anatomical_structure Oncology medicine Doxorubicin business Complication medicine.drug media_common |
| Zdroj: | Cancer. 69:2271-2275 |
| ISSN: | 1097-0142 0008-543X |
| DOI: | 10.1002/1097-0142(19920501)69:9<2271::aid-cncr2820690911>3.0.co;2-7 |
| Popis: | Metastases from cystosarcoma phyllodes are rare, and treatment generally is ineffective. Four patients were treated with ifosfamide (alone in three and combined with doxorubicin in one). Two patients had complete remissions that lasted 26 and 61+ months. One other patient had a partial response that lasted 13 months. The complete responders were both treated as soon as metastases appeared, when they had only a small volume of disease. This appears to represent a significant improvement on other described regimens for this condition, and further trials of ifosfamide are warranted. Close follow-up of patients at high risk for metastases is suggested. |
| Databáze: | OpenAIRE |
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