Interobserver reliability of methods to determine complete resection of adenomas in colonoscopy

Autor: Faraz Bishehsari, Karen Ma, Deborah Giusto, Shubha Singh, Rana Abraham, Ethan M. Ritz, David Cimbaluk, William Barge, Bana Alajati, Joshua Melson, Erica Park, John Losurdo, Saline Lee, Michael D. Brown, Jason Kramer, Mark T. DeMeo, Shriram Jakate
Rok vydání: 2020
Předmět:
Zdroj: Endoscopy. 53:1250-1255
ISSN: 1438-8812
0013-726X
DOI: 10.1055/a-1331-4446
Popis: Background Forceps margin biopsy and polypectomy specimen margins have both been used to assess for polypectomy resection adequacy. The interobserver reliability of the two methods has not been well described. Methods The interpretability of polypectomy specimens for presence of residual neoplasia at the margin was assessed by two blinded pathologists. Next, the concordance of forceps margin biopsy interpretations between three blinded pathologists was evaluated by calculation of interobserver κ. Results Rates of polypectomy specimen margin interpretability were low: 24/92 (26 %) for pathologist A, 28/92 (30.4 %) for pathologist B. Concordance of forceps margin biopsy interpretations (n = 129) between pathologists was high. Two internal pathologists showed substantial agreement in margin biopsy interpretations (κ 0.779; 95 %CL 0.543, 0.912). The concordance remained strong after biopsies were reviewed by a third, external pathologist (κ 0.829; 95 %CL 0.658, 0.924). There was complete agreement on 123/129 (95.3 %) between all three pathologists for presence of neoplasia. Conclusion The majority of polypectomy specimen margins were uninterpretable by pathologists for presence of residual neoplasia. Forceps margin biopsy shows strong interobserver reliability in adenomatous lesions.
Databáze: OpenAIRE