Measurement of 3,4 Dihydroxyphenyl Ethylene Glycol (DOPEG) in Plasma by High Performance Liquid Chromatography with Electrochemical Detection

Autor:	J. M. Gandon, J. Caroff, E. Girin, O. Curet, P. Le Bras, C. Cann-Moisan
Rok vydání:	1996
Předmět:	Reproducibility Chromatography Clinical Biochemistry Extraction (chemistry) Diol Pharmaceutical Science Biochemistry High-performance liquid chromatography Analytical Chemistry Boric acid chemistry.chemical_compound chemistry Selectivity Quantitative analysis (chemistry) Ethylene glycol
Zdroj:	Journal of Liquid Chromatography & Related Technologies. 19:3119-3124
ISSN:	1520-572X 1082-6076
DOI:	10.1080/10826079608015811
Popis:	Usually, determination of DOPEG in plasma by EC-HPLC is always performed after extraction on alumina. This paper presents an extraction on boric acid gel, with good selectivity, reproducibility. In high sensitivity conditions (0.5 nA full scale) an autosampler is used and presents two major advantages: first, the possibility of storing samples in cold conditions to preserve stability of DOPEG, second the analysis of numerous samples in pharmacological studies, for example.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::949aed2dcf5198d4496ad458ecd30d41 https://doi.org/10.1080/10826079608015811 Zobrazit plný text záznamu