Evidence for Neuroendoncrine Disturbance Following Physical Exercise in Primary Fibromyalgia Syndrome

Autor:	J.W. Boersma, E. N. Griep, E. Ronald de Kloet
Rok vydání:	1993
Předmět:	medicine.medical_specialty Primary fibromyalgia syndrome business.industry Workload Physical exercise Submaximal exercise medicine.disease Rheumatology Fibromyalgia medicine Physical therapy In patient Bicycle ergometer business Test measurement
Zdroj:	Journal of Musculoskeletal Pain. 1:217-222
ISSN:	1540-7012 1058-2452
DOI:	10.1300/j094v01n03_22
Popis:	Objective: To test pituitary-adrenal responses to hysical exercise in patients with primary fibromyalgia syndrome [PFS]. Methods: Eighteen female PFS patients [1981 Yunus criteria] and 18 matched, healthy but strictly sedentary controls performed a bicycle ergometer test with stepwise increasing workload. The first 10 couples did submaximal exercise; the next 8 couples continued until volitional exhaustion. during and after the test measurement of ACTH and cortisol was done at intervals. Results; During submaximal exercise the PFS patients, compared to the controls, displayed a [very early] significantly augmented ACTH release without a corresponding cortisol response. Within the group that performed exhaustive exercise, the 8 PFS patients achieved a lower [mean] maximum workload. At exhaustion and during early recovery ATCH and cortisol reached maximum values, which tended to be higher in PFS patients. Conclusions: PFS patients show altered pituitary-adrenal responses to physical exercise, which supports...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::948d846e0eb2ed284d97ed615b89d622 https://doi.org/10.1300/j094v01n03_22 Zobrazit plný text záznamu