Optimze the Structure of Impeller for Stirred Bioreactor

Autor: Li Kuan Zhu, Zhenlong Wang, Yu Kui Wang, Bo Yan Song
Rok vydání: 2013
Předmět:
Zdroj: Advanced Materials Research. :148-153
ISSN: 1662-8985
DOI: 10.4028/www.scientific.net/amr.694-697.148
Popis: This paper mainly makes comparative analysis on four main types of blade in stirred bioreactor by Computational Fluid Dynamics(CFD) simulation. Firstly we establish simulation method suited for stirred bioreactor, then simulate the velocity and shear force of flow field in the bioreactor. No matter from flow field mixing or shear force aspect, Elephant Ear blades is the most suitable for cell large scale culture. At last, it optimizes the installation method and angle of Elephant Ear blades. It concludes that anticlockwise rotation and 45°installation angle is the optimum.
Databáze: OpenAIRE