| Popis: |
This book chapter deals with biomedical applications of iron oxide nanoparticles (IONPs). In view of achieving proper control of particle size, shape, crystallinity, polydispersity, and finally the magnetic property, attention has to be paid to characteristics as well as advantages and disadvantages of common synthesis routes. Furthermore, proper surface functionalizations of IONPs with regard to their possible biomedical applications will be explained in detail. The second main focus is placed on several examples of biomedical applications in vitro and in vivo. Due to their unique features, it will be shown that they are adapted for a broad range of task fields. This creates very promising prospects for their further use especially in the treatment of diseases. To conclude, it will be outlined that although there are many publications stating the effectiveness of magnetic nanoparticles, data about biocompatibility and especially toxicology have yet to be collected in an appropriate manner. |
