The Effects of 6-Week Supplementation with Multicomponent Herbal Extract on Exercise Performance, Antioxidant Status and Telomere Length, and Self-Reported Side Effects in Healthy Men: A Randomized Controlled Pilot Trial
| Autor: | Nikola Todorovic, Nebojsa Maksimovic, Sergej M. Ostojic, Darinka Korovljev, József Betlehem, Laszlo Ratgeber, Pongras Acs, Valdemar Stajer, Suzana Miljkovic |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Nutrition and Dietetics Antioxidant business.industry medicine.medical_treatment Pilot trial Dietary supplement Medicine (miscellaneous) Placebo Placebo group law.invention Randomized controlled trial law Internal medicine Exercise performance Medicine Analysis of variance business |
| Zdroj: | Current Topics in Nutraceutical Research. 19:520-524 |
| ISSN: | 1540-7535 |
| DOI: | 10.37290/ctnr2641-452x.19:520-524 |
| Popis: | The main aim of this study was to examine the effects of medium-term supplementation with an eight-herbs extract on running performance, biomarkers of antioxidant status and telomere length, and self-reported outcome measures of safety events in healthy men. Ten healthy young men (age 23.1±3.2 years, weight 73.7±9.9kg, and height 179.4±8.0cm) volunteered to participate in this randomized controlled trial. The participants were allocated in a double-blind cross-over design to receive either an eight-herbs extract or placebo during a 6-week intervention period. Two-way mixed analysis of variance (treatment vs. time interaction) revealed no significant differences for exercise performance outcomes and telomere length between groups (P>0.05). Compared with placebo, P-DNA provoked a significant rise in serum total antioxidant capacity (316.0±183.4µmol/mL at baseline; 792.7±68.1µmol/mL at follow-up in the eight-herbs extract group vs. 298.1±90.7µmol/mL at follow-up in the placebo group; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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