Synthesis of new 2H-benzimidazole 1,3-dioxide derivatives analogous to separase inhibitor (Sepin-1)

Autor: Nurgali Akylbekov, A. B. Dobrynin, Alexander R. Burilov, Elena Chugunova, M. R. Gaziev, V. A. Samsonov
Rok vydání: 2017
Předmět:
Zdroj: Russian Journal of Organic Chemistry. 53:1896-1898
ISSN: 1608-3393
1070-4280
DOI: 10.1134/s1070428017120223
Popis: New biologically active 2H-benzimidazole 1,3-dioxide derivatives, analogs of Sepin-1, have been synthesized starting from benzofuroxan. Electrophilic substitution of hydrogen in the 2H-benzimidazole ring occurs at different positions, depending on the electrophile nature.
Databáze: OpenAIRE