An Efficient Synthesis of 2-(((9-Fluorenylmethoxycarbonyl)amino)methyl)benzoic Acid

Autor:	Wayne F. Daneker, Jung-Hui Sun
Rok vydání:	1998
Předmět:	chemistry.chemical_compound chemistry 9-fluorenylmethoxycarbonyl Yield (chemistry) Organic Chemistry Hydrazine Organic chemistry Protecting group Succinimidyl carbonate Benzoic acid
Zdroj:	Synthetic Communications. 28:4525-4530
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397919808004516
Popis:	An efficient, two-step syntesis of the title compound 3 in 61% overall yield is presented. The synthesis involves hydrazine removal of the N-phthalimide protecting group of α-phthalimido-o-toluic acid (6), followed by N-Fmoc formation with (9-fluorenylmethyl)succinimidyl carbonate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9471d81f79a7429cd3ad38c462b78dad https://doi.org/10.1080/00397919808004516 Zobrazit plný text záznamu