Trombosis de la arteria renal después de suspender la terapia anticoagulante en una trasplantada renal con trombofilia: Caso Clínico

Autor: Alejandro Vásquez G, Helmuth Goecke S, Armando Peña M, Jorge Vega S
Rok vydání: 2007
Předmět:
Zdroj: Revista médica de Chile. 135
ISSN: 0034-9887
Popis: Kidney graft loss because arterial thrombosis is not common andis related to risk factors such as recurrent vascular hemodialysis access thrombosis, collagen-vascular disease, repeated miscarriage, diabetes mellitus and thrombophilia. Patients havingthis last disorder have an increased risk of repeated thrombosis in successive transplants unlessthey receive anticoagulation therapy. We report a 51 year-old diabetic woman who had ahistory of recurrent vascular hemodialysis access thrombosis (both native and prosthetic) whileon dialysis and received a cadaveric donor kidney. One month after transplantation she hadaxillary vein thrombosis complicated with pulmonary embolism and received anticoagulantsfor six months. Just days after stopping the anticoagulation, she became suddenly anuric due torenal artery thrombosis and complete graft infarction. The coagulation study showed moderatehyperhomocysteinemia and a significant protein C deficiency (39%). Days after nephrectomyshe suffered a femoral vein thrombosis and anticoagulation was prescribed for life (Rev MedChile 2007; 135: 98-102).(
Databáze: OpenAIRE