Large scale screening of human sera for HCV RNA and GBV-C RNA

Autor:	Ronald Swanstrom, Kelcie Alexander, Jessica Keys, Peter A. Leone, Joseph J. Eron, Myra Brinson
Rok vydání:	2013
Předmět:	biology Molecular epidemiology Transmission (medicine) Hepacivirus Hepatitis C virus virus diseases RNA Influenza a Hepatitis C biology.organism_classification medicine.disease medicine.disease_cause Virology GB virus C Infectious Diseases Immunology medicine
Zdroj:	Journal of Medical Virology. 86:473-477
ISSN:	0146-6615
Popis:	North Carolina locates acute HIV cases by pooled nucleic acid testing of HIV- antibody negative serum samples. Here, 224 pools of 80 HIV-negative samples (N=17,920) were screened for viral RNA from HCV, GBV-C, and influenza A. No evidence of influenza A was found, but HCV and GBV-C were common (1.2% and 1.7% prevalence, respectively), demonstrating the utility of pooled testing in locating individuals that may remain undiagnosed otherwise. By sequencing positive pools, potential transmission clusters may be located as well.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::945da37fde447900c10c734e3dcba635 https://doi.org/10.1002/jmv.23829 Zobrazit plný text záznamu Plný text