Preoperative Muscle Strength Is a Predictor of Outcomes After Esophagectomy

Autor: Sally Jeanne Trufan, Nicole Lee Gower, M Hart Squires, Reilly E Shea, Jennifer H Benbow, Jonathan C. Salo, Madison E Colcord, Joshua S. Hill, Meredith E Byrne, Michael D Watson
Rok vydání: 2021
Předmět:
Zdroj: Journal of Gastrointestinal Surgery. 25:3040-3048
ISSN: 1873-4626
1091-255X
DOI: 10.1007/s11605-021-05183-y
Popis: Sarcopenia, loss of muscle mass and strength, has been associated with more frequent complications after esophagectomy. This study compared hand-grip strength, muscle mass, and intramuscular adipose tissue as predictors of postoperative outcomes and mortality after esophagectomy. Minimally invasive esophagectomy was performed on 175 patients with esophageal cancer. Skeletal muscle index and skeletal muscle density were derived from preoperative CTs. Hand-grip strength was measured using dynamometer. Univariate and multivariable analyses were performed. Preoperative hand-grip strength was normal in 91 (52%), intermediate in 43 (25%), and weak in 41 (23%) patients. Hand-grip strength was significantly correlated with both skeletal muscle index and skeletal muscle density. Postoperative pneumonia occurred in 8/41 (20%) patients with weak strength compared to 4/91 (4%) with normal strength (p = 0.006; Cochran-Armitage Test). Prolonged postoperative ventilation occurred in 11/41 (27%) patients with weak strength compared to 11/91 (12%) with normal strength (p = 0.036). Median length of stay was 9 days in patients with weak strength compared to 7 days for those with normal strength (p = 0.005; Kruskal–Wallis Test). Discharge to non-home location occurred in 15/41 (37%) with weak strength compared to 8/91 (9%) with normal strength (p
Databáze: OpenAIRE
Externí odkaz: