| Autor: |
E. Olajide, B.A. Alaba, O.A. Makinde, K.Y. Suleiman, S.A. Amid, B. S. Okediran |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Assiut Veterinary Medical Journal. 67:15-20 |
| ISSN: |
2314-5226 |
| DOI: |
10.21608/avmj.2021.188715 |
| Popis: |
Welding fumes are composed of fine and ultrafine particles, which when it gained access to the body system either via inhalation or as food or water contaminants can elicit various haematological and biochemical changes. In order to determine the haematological changes elicited by welding fumes and it’s mitigation by ascorbic acid, a total of fifteen male Wistar rats were randomly divided into three groups (A, B and C) of five animals per group. Group A served as the control while group B were kept in enclosed welding environment for adequate inhalation of the welding fume. Group C were equally kept in the enclosed welding environment but were daily orally administered 100mg of ascorbic acid for two weeks. At the end of two weeks of exposure, blood samples were obtained for haematological analyses. It was observed that exposure to the welding fumes predisposes the rats to macrocytic hypochromic anaemia and stress with evidence of neutrophilia and lymphopenia. These observed haematological perturbations were reversed by ascorbic acid back similar to that of the control group. It can be concluded that haematological perturbation induced by welding fume can be mitigated effectively by ascorbic acid without any deleterious effects. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
