Modern Conceptions of Blood Clotting

Autor: J. W. Pickering
Rok vydání: 1925
Předmět:
Zdroj: Journal of Experimental Biology. 2:397-411
ISSN: 1477-9145
0022-0949
Popis: Despite the large number of researches which have been made on blood coagulation, no single one of the many theories advanced satisfies the criterion of a tenable hypothesis in which all known facts should be correlated. A better understanding of the fluidity and clotting of blood should lead to important results. On the practical side, we may hope for the elucidation of thrombosis—the formation of clots in the vessels—of the lack of coagulability in hæmophilia, of the changes in plasma during shock, and of the fatal intra-vascular clotting caused by certain snake venoms. On the theoretical side, light should be thrown on the reactions of colloids, on the mechanisms of immunity and of susceptibility, and possibly on the problems of genetics, as hæmophilia is transmitted from parent to offspring, and the existence of homologous bloods often depends on family relationship. In this paper the current theories of blood coagulation will be reviewed briefly from the standpoint of investigations made in collaboration with my friends Drs Hewitt, de Souza, and Taylor,1-9 and evidence for a simpler view will be presented.
Databáze: OpenAIRE