Involvement of fibronectin and interacting serum components in the regulation of activity of human natural killer cells

Autor: D. V. Kuyavskaya, I. A. Tarkhanova, A. Ya. Kul'berg, E. E. Babaeva, S. B. Cheknev, Bartova Lm
Rok vydání: 1994
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 118:737-742
ISSN: 1573-8221
0007-4888
Popis: The cytotoxic activity of natural killer cells and the intensity of conjugate formation are studiedin vitro in the natural cytotoxicity reaction against3H-uridine-labeled human erythromyeloleukotic cells K-562 in the presence of fibronectin, γ-globulin, and fibronectin/γ-globulin combination. It is demonstrated that fibronectin does not change natural cytotoxicity, γ-globulin increases the activity of human natural killer cells, and the fibronectin — γ-globulin combination increases both the intensity of conjugate formation and the cytotoxic activity of natural killer cells.
Databáze: OpenAIRE