Involvement of fibronectin and interacting serum components in the regulation of activity of human natural killer cells
Autor: | D. V. Kuyavskaya, I. A. Tarkhanova, A. Ya. Kul'berg, E. E. Babaeva, S. B. Cheknev, Bartova Lm |
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Rok vydání: | 1994 |
Předmět: | |
Zdroj: | Bulletin of Experimental Biology and Medicine. 118:737-742 |
ISSN: | 1573-8221 0007-4888 |
Popis: | The cytotoxic activity of natural killer cells and the intensity of conjugate formation are studiedin vitro in the natural cytotoxicity reaction against3H-uridine-labeled human erythromyeloleukotic cells K-562 in the presence of fibronectin, γ-globulin, and fibronectin/γ-globulin combination. It is demonstrated that fibronectin does not change natural cytotoxicity, γ-globulin increases the activity of human natural killer cells, and the fibronectin — γ-globulin combination increases both the intensity of conjugate formation and the cytotoxic activity of natural killer cells. |
Databáze: | OpenAIRE |
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