ChemInform Abstract: Convenient, One-Step Syntheses of 2-Fluoroveratrole and 2-Fluoroveratraldehyde

Autor:	Mccowan Jefferson Ray, Norton P. Peet, James R. McCarthy, Shyam Sunder
Rok vydání:	1987
Předmět:	chemistry.chemical_compound Chemistry Reagent Fluorine Veratraldehyde chemistry.chemical_element One-Step General Medicine Perchloryl fluoride Combinatorial chemistry
Zdroj:	ChemInform. 18
ISSN:	0931-7597
DOI:	10.1002/chin.198714135
Popis:	Metalated veratraldehyde and veratrole were quenched with perchloryl fluoride to provide one-step syntheses of 2-fluoroveratraldehyde and 2-fluoroveratrole, respectively. Previous syntheses of these precursors to 2-fluorodopamine and 5-fluoronorepinephrine are multi-step processess which involve introduction of fluorine at an early stage. Perchloryl fluoride is a potentially hazardous reagent, and should be used only on an appropriate (millimolar) scale with precautions.
Databáze:	OpenAIRE
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