Use of iPad technology to determine cancer patient-reported preferences for and understanding of pharmacogenetic testing (PGT)

Autor: Chongya Niu, Geoffrey Liu, Jodie Villeneuve, Christine Lam, Osvaldo Epsin-Garcia, Jodie Jenkinson, Petra Martin, Henrique Hon, Wei Xu, Sinead Cuffe, Dan Pringle, Memori Otsuka, Ravi M. Shani, Shabbir Alibbhai, Rebecca Charow, Catherine Brown, Mary Mahler
Rok vydání: 2012
Předmět:
Zdroj: Journal of Clinical Oncology. 30:319-319
ISSN: 1527-7755
0732-183X
DOI: 10.1200/jco.2012.30.34_suppl.319
Popis: 319 Background: PGT in oncology can be used to predict the efficacy and toxicity of a particular treatment in an individual. Previous work by our group has demonstrated that among cancer patients willing to undergo chemotherapy, >98% wanted PGT testing if it could identify patients who would respond to chemo. However, in the original study using a paper questionnaire, 22% of patients did not understand the concept of PGT and its clinical implications. Therefore, we have devised a simpler, more visual questionnaire in electronic format using iPad technology and simple animations. We are assessing if patient understanding using this format is increased and also if patients prefer completing the survey with this novel technology. Methods: An interim analysis of a broad cross-section of cancer patients using an iPad was performed. PGT questions related to hypothetical efficacy, toxicity, time to test results, willingness to pay as well as understanding of PGT scenarios were assessed. Results: 135 cancer patients (87% adjuvant, 12% metastatic; 27% breast, 25% colon, 22% heme malignancy, 23% other) attending Princess Margaret Hosptial participated. 85% of patients accepted chemo that had a 5% absolute improvement in survival and
Databáze: OpenAIRE