Lower Baseline Glycemia Reduces Apparent Oral Agent Glucose-Lowering Efficacy
| Autor: | Silvio E. Inzucchi, Regina Dodis, Zachary T. Bloomgarden, Eric S. Holmboe, Catherine M. Viscoli |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Advanced and Specialized Nursing
Drug medicine.medical_specialty endocrine system diseases business.industry Endocrinology Diabetes and Metabolism media_common.quotation_subject nutritional and metabolic diseases Disease medicine.disease Efficacy Internal medicine Diabetes mellitus Epidemiology Covariate Internal Medicine medicine Meta-regression Baseline (configuration management) business media_common |
| Zdroj: | Diabetes Care. 29:2137-2139 |
| ISSN: | 1935-5548 0149-5992 |
| DOI: | 10.2337/dc06-1120 |
| Popis: | Perusal of advertisements for oral hypoglycemic agents in this and many other medical journals shows an emphasis on the absolute reduction in HbA1c (A1C). Evidence linking reduction in A1C in diabetic patients to prevention of macrovascular events is weak. However, epidemiological evidence suggests that the risk for cardiovascular disease in this group may actually begin at A1C concentrations well within the normal range (1). This association has led a number of professional organizations to recommend that A1C levels be brought to levels |
| Databáze: | OpenAIRE |
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