Quantitative correlation of lumbar foraminal stenosis with local morphological metrics

Autor: Andrew P. Klein, Kevin M. Koch, Benjamin I. Meyer, Vimal Gunasekaran, Dustin Hejdak
Rok vydání: 2021
Předmět:
Zdroj: European Spine Journal. 30:3319-3323
ISSN: 1432-0932
0940-6719
DOI: 10.1007/s00586-021-06944-8
Popis: Clinical evaluation of lumbar foraminal stenosis typically includes qualitative assessments of perineural epidural fat content around the spinal nerve root and evaluation of nerve root impingement. The present study investigates the use of several morphological MRI-derived metrics as quantitative predictors of foraminal stenosis grade. 62 adult patients that underwent lumbar spine MRI evaluation over a 1-month duration in 2018 were included in the analysis. Radiological gradings of stenosis were captured from the existing clinical electronic medical record. Clinical gradings were recorded using a 0–5 scale: 0 = no stenosis, 1 = mild stenosis, 2 = mild-moderate stenosis, 3 = moderate stenosis, 4 = moderate-severe stenosis, 5 = severe stenosis. Quantitative measures of perineural epidural fat volume, nerve root cross-sectional area, and lumbar pedicle length were derived from T1 weighted sagittal spine MRI on each side of all lumbar levels. Spearman correlations of each measured metric at each level were then computed against the stenosis gradings. A total of 347 volumetric segmentation and radiological foraminal stenosis grade sets were derived from the 62-subject study cohort. Statistical analysis revealed significant correlations (p
Databáze: OpenAIRE
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