ChemInform Abstract: Novel Heterocyclization of Hydrazinopyridazinones with Dimethyl Acetylenedicarboxylate with Dehydrogenation and Rearrangement

Autor:	Tetsuo Yamasaki, Tadashi Okawara, Mitsuru Furukawa, T. Yamada, Eiji Kawaminami
Rok vydání:	2010
Předmět:	Dimethyl acetylenedicarboxylate chemistry.chemical_compound Chemistry Dehydrogenation General Medicine Medicinal chemistry
Zdroj:	ChemInform. 22
ISSN:	0931-7597
DOI:	10.1002/chin.199133196
Popis:	5-Hydrazinopyridazin-3(2H)-ones 1 reacted with dimethyl acetylenedicarboxylate 2 to give 4,6-dihydropyridazino[4,5-c] pyridazin-5-(1H)-ones 3 by cyclization with dehydrogenation. On the other hand, the reaction of 4-bromo-5-hydrazino- and 5-bromo-4-hydrazinopyridazin-3(2H)-ones 8 and 10 with diester 2 resulted in the novel cyclization with rearrangement to give compounds 3 and 9 together with the expected cyclization products.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::93e67efa1a7122ae64ac941cd0798d45 https://doi.org/10.1002/chin.199133196 Zobrazit plný text záznamu Plný text