Synthesis and antibacterial activity of some new hydrazones
| Autor: | T. Sri Swaroopini, S. Zaheera, T. Naga Lakshmi, S. Kamar Jaha, R. Siva Satyanandam, Mithun Rudrapal |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
chemistry.chemical_classification
biology Pseudomonas aeruginosa Chemistry Organic Chemistry Hydrazone Bacillus subtilis medicine.disease_cause biology.organism_classification Salmonella typhi Proteus mirabilis Staphylococcus aureus medicine bacteria Organic chemistry General Pharmacology Toxicology and Pharmaceutics Antibacterial activity Escherichia coli |
| Zdroj: | Medicinal Chemistry Research. 22:2840-2846 |
| ISSN: | 1554-8120 1054-2523 |
| DOI: | 10.1007/s00044-012-0278-5 |
| Popis: | New hydrazone derivatives were synthesized by the condensation of some selected heteroaromatic hydrazines with appropriate aromatic ketones at high temperature (100 °C). The structures of the synthesized compounds were established by elemental (CHN) and spectral (IR, 1HNMR, and Mass) analysis. The synthesized compounds were screened for their antibacterial (Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Proteus mirabilis) activities, which reveal that all the compounds possess activity against all the tested organisms. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink