Fluorometholone-Gentamicin Eye Drops vs Fluorometholone-Neomycin Eye Drops Following Cataract Surgery†
| Autor: | M. Froböse, P. Sunder Raj, P. D. Steinbach |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Conjunctival hyperaemia
Fluorometholone / Neomycin medicine.medical_specialty genetic structures business.industry medicine.medical_treatment General Medicine Cataract surgery eye diseases Pharmacotherapy Postoperative visit Ophthalmology medicine Pharmacology (medical) Gentamicin sense organs business Ocular inflammation Fluorometholone medicine.drug |
| Zdroj: | Clinical Drug Investigation. 13:242-246 |
| ISSN: | 1173-2563 |
| Popis: | This was a prospective, randomised, investigator-masked, parallel-group, single centre study that was performed to compare fluorometholone-gentamicin eye drops with fluorometholone-neomycin eye drops in the control of ocular inflammation after cataract surgery. Ocular examinations were carried out preoperatively and postoperatively on days 1 (baseline), 3 and 6. 60 patients (30 in each treatment group) of both genders undergoing cataract-lens implant surgery for visually disabling cataract were enrolled in the study. The baseline parameters were similar in the two study groups. At day 6 after treatment (final postoperative visit), cells in the anterior chamber (p = 0.004) and conjunctival hyperaemia (p = 0.02) were statistically significantly less with fluorometholone-gentamicin compared with fluorometholone-neomycin. Both treatments were equally well tolerated. In conclusion, this study demonstrated that fluorometholone-gentamicin eye drops were more effective than fluorometholone-neomycin eye drops in the control of ocular inflammation after cataract surgery. |
| Databáze: | OpenAIRE |
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