A canine model of chronic ischemic heart failure

Autor:	Muhammad S. Khan, Douglas Smego, Yuki Ishidoya, Annie M. Hirahara, Emmanuel Offei, Martha S. Ruiz Castillo, Omar Gharbia, Hui Li, Joseph A. Palatinus, Lauren Krueger, TingTing Hong, Guillaume L. Hoareau, Ravi Ranjan, Craig H. Selzman, Robin M. Shaw, Derek J. Dosdall
Rok vydání:	2023
Předmět:	Physiology Physiology (medical) Cardiology and Cardiovascular Medicine
Zdroj:	American Journal of Physiology-Heart and Circulatory Physiology. 324:H751-H761
ISSN:	1522-1539 0363-6135
Popis:	The novel total left anterior descending devascularization (TLD) approach in a canine ischemic heart failure model limits collateral flow in the ischemic zone and provides excellent early survival and repeatable development of chronic ischemic heart failure in the canine heart. This work provides a consistent large animal model for investigating heart failure mechanisms and testing novel therapeutics.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::93c103a877b2047a10befdc5c1d643eb https://doi.org/10.1152/ajpheart.00647.2022 Zobrazit plný text záznamu