Catatonia in systemic lupus erythematosus: case based review
| Autor: | Hafis Muhammed, Ramnath Misra, T. G. Sundaram, Amita Aggarwal, Latika Gupta, Able Lawrence |
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| Rok vydání: | 2021 |
| Předmět: |
Acute cutaneous lupus erythematosus
medicine.medical_specialty Catatonia business.industry medicine.medical_treatment Stupor Immunology Immunosuppression medicine.disease Pancytopenia Dermatology Toxic epidermal necrolysis Electroconvulsive therapy Rheumatology immune system diseases Macrophage activation syndrome medicine Immunology and Allergy medicine.symptom skin and connective tissue diseases business |
| Zdroj: | Rheumatology International. 42:1461-1476 |
| ISSN: | 1437-160X |
| DOI: | 10.1007/s00296-021-05006-y |
| Popis: | Catatonia is a rare psychomotor syndrome characterized by stupor, posturing and echophenomena. It can be associated with schizophrenia, infections, drugs and autoimmune causes like anti N-methyl D-aspartate (NMDA) receptor encephalitis and systemic lupus erythematosus (SLE). Here we report two cases of systemic lupus erythematosus with catatonia, who improved with immunosuppressive treatment and review the cases described in the literature. The first case presented with fever, pancytopenia, toxic epidermal necrolysis (TEN)-like rash and later developed catatonia and macrophage activation syndrome (MAS). The second case presented with acute cutaneous lupus erythematosus (ACLE), fever, alopecia, polyarthralgias, nephritis, cytopenias along with catatonia. Successful management of this syndrome requires prompt recognition and treatment with immunosuppression as well as benzodiazepines with or without electroconvulsive therapy (ECT). |
| Databáze: | OpenAIRE |
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