Design and synthesis of oxacycles from norbornene derivatives via ring-opening metathesis and ring-rearrangement metathesis
| Autor: | Ongolu Ravikumar, Gaddamedi Sreevani, Sambasivarao Kotha |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Cyclopentadiene
010405 organic chemistry Stereochemistry Organic Chemistry 010402 general chemistry Ring (chemistry) Metathesis 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound Oxygen atom chemistry Drug Discovery Ring-opening metathesis polymerisation Acyclic diene metathesis Norbornene |
| Zdroj: | Tetrahedron. 72:6611-6615 |
| ISSN: | 0040-4020 |
| DOI: | 10.1016/j.tet.2016.08.073 |
| Popis: | Norbornene derivatives containing oxygen atom(s) are found to undergo ring-rearrangement metathesis sequence to deliver cyclic ethers. Here, we have established a simple, efficient and an atom-economic process for the synthesis of fused and spiro-oxacyclic compounds starting with cyclopentadiene. Compounds prepared in this study are difficult to assemble by conventional retrosynthetic routes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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