Dahuang Zhechong Pill (大黄虫丸) containing serum inhibited platelet-derived growth factor-stimulated vascular smooth muscle cells proliferation by inducing G1 arrest partly via suppressing protein kinase C α-Extracellular regulated kinase 1/2 signaling pathway
Autor: | Juntian Liu, Peipei Lu, Na Liu, Yuanyuan Ji |
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Rok vydání: | 2011 |
Předmět: |
Platelet-derived growth factor
Vascular smooth muscle biology Kinase Growth factor medicine.medical_treatment General Medicine Cell biology chemistry.chemical_compound Complementary and alternative medicine chemistry biology.protein medicine Extracellular Pharmacology (medical) Signal transduction Protein kinase C Platelet-derived growth factor receptor |
Zdroj: | Chinese Journal of Integrative Medicine. 18:371-377 |
ISSN: | 1993-0402 1672-0415 |
DOI: | 10.1007/s11655-011-0696-0 |
Popis: | Objective To investigate effects of Dahuang Zhechong Pill (大黄{ie371-1}虫丸, DHZCP) on the cell cycle and the related signal pathways in vascular smooth muscle cells (VSMCs) stimulated by platelet-derived growth factor (PDGF) with the method of serum pharmacology. |
Databáze: | OpenAIRE |
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