5-Formyl-2-furylboronic Acid as a Versatile Bifunctional Reagent for the Synthesis of π-Extended Heteroarylfuran Systems

Autor:	Brian Tarbit, Martin R. Bryce, Paul R. Parry
Rok vydání:	2003
Předmět:	Chemistry Wittig reaction Bifunctional reagent General Medicine Combinatorial chemistry Thiophene derivatives
Zdroj:	ChemInform. 34
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200336088
Popis:	5-Formyl-2-furylboronic acid reacts cleanly with a range of heteroaryl bromides under Suzuki–Miyaura cross-coupling conditions to produce 2-formyl-5-heteroarylfuran derivatives. Subsequent Wittig olefination reactions afford π-conjugated alkene–pyridyl–furan derivatives.
Databáze:	OpenAIRE
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