Collagen/aminated MWCNTs nanocomposites for biomedical applications
| Autor: | Jin Mei He, Ali Nabipour Chakoli, Yu Dong Huang |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
Materials science Nanocomposite Coagulation time Aromatic amine 02 engineering and technology Carbon nanotube engineering.material 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences law.invention Chemical bond Chemical engineering X-ray photoelectron spectroscopy chemistry Mechanics of Materials law Materials Chemistry engineering General Materials Science Biopolymer 0210 nano-technology Dispersion (chemistry) |
| Zdroj: | Materials Today Communications. 15:128-133 |
| ISSN: | 2352-4928 |
| DOI: | 10.1016/j.mtcomm.2018.03.003 |
| Popis: | Collagen (COL) is a biopolymer that widely used for a number of medical treatments especially haemostatic applications. To enhance the medical performance of COL and explore an alternative approach, its modification using Carbon Nanotubes is considered. To treat a valuable cross linking and chemical bonding, aminated MWCNTs (MWCNT-NH2)s, which introduced the aromatic amine on the side wall of MWCNTs, were jointed to the COL sponges (COLSP)s. To explore the origin of this behaviour, dispersion of MWCNT-NH2s on COLSPs and their interfacial interactions were investigated by SEM, FT-IR and XPS. The analytical results show a relatively strong interaction existed between aminated MWCNTs and the sidewall of COLSPs. The hydrophilicity test results revealed significant increment in water uptake of MWCNT-NH2s/COL composites with increasing the concentration of MWCNT-NH2s until 13 wt%. Additionally, the addition of aminated MWCNTs decreases the coagulation time of anti coagulated rabbit blood, indicating that the MWCNT-NH2s/COLSPs have significant pro-coagulant activity. Due to agglomeration of MWCNT-NH2s in solution, also, the surface limitation of sponges, increment in concentration of MWCNT-NH2s up to 14 wt% is not adequate. This study promises that the MWCNT-NH2s cross-linked COL fibres present mechanical strength significantly higher than that of neat COL fibres. |
| Databáze: | OpenAIRE |
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