PRECLINICAL AND CLINICAL STUDY OF EXTRACELLULAR DNA IN CANCER AND OTHER DISEASES ASSOCIATED WITH APOPTOSIS DISORDER

Autor: Irina Vasileva, Viktor Bespalov
Rok vydání: 2018
Předmět:
Zdroj: Problems in oncology. 64:435-439
ISSN: 0507-3758
DOI: 10.37469/0507-3758-2018-64-3-435-439
Popis: Oncological diseases at all stages of carcinogenesis are accompanied by violation of apoptosis processes. Drug and radiotherapy activates the apoptosis of tumor cells. This study presents the results of extracellular DNA changes after exposure to ionizing radiation and low-frequency noise are presented, administration of vitamins; in animals with benign prostatic hyperplasia, with ovarian cancer; in clinical studies in patients with chronic obstructive pulmonary disease, and in acute disorders of cerebral circulation. The possibilities of determination of extracellular DNA for the evaluation of the action of carcinogens, the complex diagnosis of precancerous diseases, the progression of precancerous diseases and malignant tumors are considered.
Databáze: OpenAIRE