Comparison of Fluctuations of Oxygen Tension in FSA, 9L, and R3230AC Tumors in Rats

Autor:	L. Isabel Cárdenas-Navia, Rod D. Braun, Kristina H. Lewis, Mark W. Dewhirst
Rok vydání:	2003
Předmět:	Tumor hypoxia business.industry medicine.medical_treatment Intermittent hypoxia Tumor Oxygenation Hypoxia (medical) Tumor response Oxygen tension Radiation therapy Acute hypoxia Cancer research medicine medicine.symptom business
Zdroj:	Advances in Experimental Medicine and Biology ISBN: 9781461349648
DOI:	10.1007/978-1-4615-0205-0_2
Popis:	Tumor hypoxia is known to reduce the sensitivity of tumors to radiation therapy. Although hypoxia plays a major role in tumor response to therapy, its exact causes are still unknown. In particular, the temporal characteristics of acute hypoxia have not been extensively explored. Previous publications have shown that P0 in tumors changes over time, and that these changes may play an important and potentially radiobiologically significant role in tumor hypoxia. This study examines the kinetics of PO fluctuations in FSA and 9L, and seeks to discover if there are differences in the power and frequency of these fluctuations between different tumor lines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9329e2b5e76c2a0c9672c3c0899e91a4 https://doi.org/10.1007/978-1-4615-0205-0_2 Zobrazit plný text záznamu