ChemInform Abstract: A Novel Approach to Tricyclic Pharmaceuticals via Directed Dilithiation of Diaryl Compounds

Autor: Anu Chopra, Vladimir B. Birman, Craig A. Ogle
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 27
ISSN: 0931-7597
Popis: Tricyclic compounds were prepared using a novel approach based on the reaction between dilithio-diphenyl ether with appropriately substituted esters. The pharmaceutical drug, clopipazan, and its corresponding deschloro analog were synthesized utilizing this approach.
Databáze: OpenAIRE