Breath testing as potential colorectal cancer screening tool
| Autor: | Hossam Haick, Konrads Funka, Guntis Ancans, Ivars Tolmanis, Aigars Vanags, Ilze Kikuste, Haitham Amal, Marcis Leja, Limas Kupčinskas, Arnis Kiršners, Ieva Lasina, Armands Sivins, Roberts Skapars |
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| Rok vydání: | 2015 |
| Předmět: |
Cancer Research
medicine.medical_specialty Pathology medicine.diagnostic_test Adenoma Crc screening Colorectal cancer business.industry Colonoscopy medicine.disease Gastroenterology 03 medical and health sciences 0302 clinical medicine Breath testing Oncology Colorectal cancer screening 030220 oncology & carcinogenesis Internal medicine medicine 030211 gastroenterology & hepatology Screening tool business |
| Zdroj: | International Journal of Cancer. 138:229-236 |
| ISSN: | 0020-7136 |
| Popis: | Although colorectal cancer (CRC) screening is included in organized programs of many countries worldwide, there is still a place for better screening tools. In this study, 418 breath samples were collected from 65 patients with CRC, 22 with advanced or nonadvanced adenomas, and 122 control cases. All patients, including the controls, had undergone colonoscopy. The samples were analysed with two different techniques. The first technique relied on gas chromatography coupled with mass spectrometry (GC-MS) for identification and quantification of volatile organic compounds (VOCs). The T-test was used to identify significant VOCs (p values |
| Databáze: | OpenAIRE |
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