Purification and identification of intestinal mucosal cell proliferation-promoting peptides from Crassostrea hongkongensis
| Autor: | Huili Sun, Xin Chen, Jianyu Pan, Bingna Cai, Peng Wan, Deke Chen, Hua Chen |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Oyster
030309 nutrition & dietetics medicine.medical_treatment Peptide Biochemistry Industrial and Manufacturing Engineering 03 medical and health sciences chemistry.chemical_compound 0404 agricultural biotechnology Pepsin biology.animal medicine chemistry.chemical_classification 0303 health sciences Protease biology Molecular mass 04 agricultural and veterinary sciences General Chemistry Trypsin 040401 food science Intestinal epithelium Papain chemistry biology.protein Food Science Biotechnology medicine.drug |
| Zdroj: | European Food Research and Technology. 245:631-642 |
| ISSN: | 1438-2385 1438-2377 |
| Popis: | Oyster peptides, together with polysaccharides, were found to protect the intestinal mucosal barrier against the harmful effects of 5-FU chemotherapy on rats in our previous study. However, whether oyster (Crassostrea hongkongensis) peptide can promote intestinal epithelia cell proliferation and migration alone is unknown. In this paper, oyster tissue was hydrolyzed using pepsin, trypsin, papain, bromelain, neutrase, flavorzyme, and alcalase protease. Among the hydrolysates that produced by trypsin showed the highest promoting effect on intestinal epithelia cell (IEC-6) proliferation and was fractionated into three molecular weight ultra-filtrates of > 10, 10–5, and |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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