Non-Hodgkin's lymphoma in Jilin Province, China. Part 1. A comparison of NHL of Jilin Province and Akita Prefecture, Japan
| Autor: | Masahiro Saitoh, Ya Jie Zhang, Yoshiyuki Uyesaka, Tsutomu Watanuki |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
endocrine system
Veterinary medicine Working Formulation endocrine system diseases Incidence (epidemiology) Mean age Biology University hospital medicine.disease Non-Hodgkin's lymphoma Intestinal inflammation medicine Age distribution Male to female hormones hormone substitutes and hormone antagonists |
| Zdroj: | Journal of the Japan Society of the Reticuloendothelial System. 33:69-80 |
| ISSN: | 1883-6801 0386-9725 |
| DOI: | 10.3960/jslrt1961.33.69 |
| Popis: | In order to elucidate the epidemio-etiological factors of NHL in Jilin Province, a comparative study on 116 cases of the 3rd Hospital of Norman Bethune University of Medical Science (1977-1990) and 252 cases of the Akita University Hospital (1972-1992) was histologically and immunohistochemically performed, applying the modified classification of the Working Formulation by Nathwani. (Jilin Province and Akita Prefecture which respectively situated at lat. 44° and 40° N. and both have great agricultural activities.) The results obtained were as follows: 1. Overall mean age was 39.0 and 55.2 years in Jilin and in Akita, respectively. The age distribution curve of Jilin showed a bimodal pattern with peaks at 20-29 and 40-59 years of age, and the analysis in Akita revealed a peak at 50-69 years. 2. The male to female ratio was 2.9:1 in Jilin and 1.6:1 in Akita. 3. In Jilin, the commonest affected site was the intestine, particularly the small intestine, and mesenteric lymph node. The higher incidence of the intestine in Jilin suggests intestinal inflammation (by infection of pathogenic organisms, or intake of water or vegetables contaminated by agricultural chemicals) as an important risk factor. In Akita, cervical lymph node and Waldeyer's ring were the two commonest sites. 4. The incidence of follicular lymphomas in Jilin was higher than that in Akita, because of its higher incidence in the small intestine cases. The incidence of diffuse lymphomas in Jilin was similar to that in Akita. 5. The B/T ratio indicated 4.0:1 and 2.8:1 in Jilin and in Akita, respectively. DLnc was the commonest histological subtype of B cell lymphomas both in Jilin and Akita, which even prominent in Jilin. The incidence of T cell lymphomas in Jilin was slightly lower than that in Akita, possibly due to absence of the case of ATLL subtype in Jilin. |
| Databáze: | OpenAIRE |
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