Insuffisance rénale chronique au cours de la drépanocytose : une analyse rétrospective de 100 patients adultes drépanocytaires majeurs d’Afrique noire
| Autor: | Clément Ackoundou-N’Guessan, Cyr Monley Guei, Gustave Koffi, Serges Konan, Pessa Albert Coulibaly, Mélanie Weu Tia, Sita Nzoue, Serges Gbekedi, Daze Apollinaire Gnionsahe, Delphine Amélie Lagou |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Univariate analysis business.industry 030232 urology & nephrology Renal function Retrospective cohort study 030204 cardiovascular system & hematology Logistic regression Gastroenterology 03 medical and health sciences 0302 clinical medicine Maintenance therapy Nephrology Internal medicine Epidemiology medicine Population study business Glomerular hyperfiltration |
| Zdroj: | Néphrologie & Thérapeutique. 12:149-155 |
| ISSN: | 1769-7255 |
| Popis: | The prevalence of chronic renal failure (CRF) in sickle cell disease (SCD) patients could vary from one country to another depending on the modalities of management. The aim of the present study was to appreciate the epidemiology of CRF in SCD patients from black Africa in order to search for promoting factors. One hundred SCD adult patients have been considered for the study. The glomerular filtration rate (GFR) has been estimated according to the CKD-EPI formula. Three groups of patients have been identified according to the value of their GFR. The mean age of the patients was 30.84±8.26 years. Male gender has represented 51% of the study population. The mean GFR value was 175.4±86.2 mL/min/1.73 m(2). The prevalence of CRF was 11%. About 3% of them had severe CRF. Subjects with normal GFR were 20%. Subjects with glomerular hyperfiltration (HF) were 69%. By univariate analysis, when subjects with HF were compared with those presenting normal GFR, the following factors have appeared to be significantly associated: female gender (female 60.9% versus male 39.1%; P 60 kg; 59.9±9.41 kg; P 30 years; OR=0.12 [CI95% 0.03-04]; P 60 kg; OR=0.19 [CI95% 0.05-0.72]; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect