Effect of conditioned medium of neonatal rat hepatocytes on mixed culture of kupffer cells and fibroblast-like liver cells

Autor:	Stvolinskaia Ns, Tabuntsova Si, Korovkin Bf
Rok vydání:	1991
Předmět:	Neonatal rat Nucleolus Chemistry General Medicine digestive system General Biochemistry Genetics and Molecular Biology Cell biology medicine.anatomical_structure Mixed culture Cell culture Conditioned medium medicine Fibroblast Cells size Mitosis
Zdroj:	Bulletin of Experimental Biology and Medicine. 112:1655-1658
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00840440
Popis:	The study was carried out on primary coculture Kupffer cells and liver fibroblasts of newborn and mature rats. At first Kupffer cells and liver fibroblasts were taken on the equal quantity. There were observed significant decrease of Kupffer cells quantity and fibroblasts death after 4-5 days in coculture. Mitotic and functional activity liver fibroblasts, adhesion of Kupffer cells were increased by the using of conditioned medium of newborn rat hepatocytes. The rise of mitotic activity of liver fibroblasts and quantity of nucleolus in their nuclei forestalls of the increase Kupffer cells size, appearing of Kupffer cells with some nuclei.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::92ea808e4398d4936ece450e46a672db https://doi.org/10.1007/bf00840440 Zobrazit plný text záznamu Full text from SpringerLink