The Novel Biomarker Growth Differentiation Factor-15 in Patients with Chronic Heart Failure at a Heart Failure Clinic in the Asia-Pacific Region: A Prospective Observational Study

Autor: Yee Ling Cham, Alan Yean Yip Fong, Joshua Bui Kiong Chung, Hwei Sung Ling, Ing Xiang Pang, Lee Karl Thien, Han Bin Chow, Issac En Zhe Chan, Francis Eng Pbeng Shu, Chen Ting Tan, Keng Tat Koh, Yen Yee Oon, Asri Said, Tiong Kiam Ong
Rok vydání: 2023
Zdroj: Journal of Asian Pacific Society of Cardiology. 2
ISSN: 2754-0650
Popis: Background: Growth differentiation factor-15 (GDF-15) is an emerging prognostic biomarker in heart failure (HF). However, there are limited data on its role in HF patients in southeast Asia. This prospective observational study investigated the association between GDF-15 and various clinical parameters, and its role in predicting all-cause mortality. Methods: 160 patients with chronic HF and reduced left ventricular ejection fraction (LVEF) enrolled between October 2020 and April 2021. At study entry, baseline GDF-15 and N-terminal pro B-type natriuretic peptide (NT-proBNP) were evaluated. Patients were followed up per clinical routine. Results: The median GDF-15 was 1,715 ng/l. Patients were divided into two groups: GDF-15
Databáze: OpenAIRE