Comparison between intra-articular bupivacaine with epinephrine and epinephrine alone on short-term and long-term pain after knee arthroscopic surgery under general anesthesia in day-surgery patients

Autor: J. Toivonen, V.-M. Pitko, Per H. Rosenberg
Rok vydání: 2002
Předmět:
Zdroj: Acta Anaesthesiologica Scandinavica. 46:435-440
ISSN: 0001-5172
Popis: Background: Postarthroscopy analgesia has been provided with intra-articular bupivacaine, but reported results are conflicting regarding efficacy and the duration of analgesia. The immediate and long-term effects of intra-articular bupivacaine with epinephrine after arthroscopic knee surgery were therefore studied in a day surgery setting. Methods: 120 ASA I–II patients scheduled for arthroscopic knee surgery were given general anesthesia with spontaneous breathing via a laryngeal mask. In a randomized and blinded fashion half of them received, at the end of surgery, intra-articularly 20 mL 0.5% bupivacaine with epinephrine (B + E-group) and the other half 20 mL saline with epinephrine (S + E-group). All patients received ketoprofen 100 mg i.v. during surgery and another 100 mg 2–3 h postoperatively. The patients were observed for about 4.5 h in the day surgery unit before discharge. Results: The results showed that in comparison with the S + E-group, significantly fewer patients in the B + E-group needed analgesics (P
Databáze: OpenAIRE