Two novel iridoid derivatives isolated from Phlomis likiangensis

Autor:	Jing-Kun Wang, Yun-Biao Li, Xiao-Hui Li, Yuan-Chang Duan, Tao Cui, Zhaoyun Zhu, Mei Shuangxi, Xu-Hong Li, De-Huan Fu, Li-He Lu
Rok vydání:	2018
Předmět:	Iridoid biology 010405 organic chemistry Stereochemistry medicine.drug_class Chemistry Organic Chemistry biology.organism_classification 01 natural sciences Biochemistry 0104 chemical sciences 010404 medicinal & biomolecular chemistry Phlomis Drug Discovery medicine
Zdroj:	Tetrahedron Letters. 59:995-998
ISSN:	0040-4039
Popis:	The extract of the aerial and underground parts of Phlomis likiangensis afforded two new iridoid derivatives, namely as phloloside H (1) and phloline (2), along with four known compounds (3–6), and compound 2 was a novel normonoterpene. Their structures were elucidated on the basis of spectroscopic studies and chemical methods. Six compounds were assayed for cytotoxic, antibacterial and antioxidative activities, but were either inactive or very weakly active.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::92dd52b6c035b7c70ca2ad3bbfb0a546 https://doi.org/10.1016/j.tetlet.2018.01.076 Zobrazit plný text záznamu Full Text from ScienceDirect