The role of portal pressure in the severity of bleeding in portal hypertensive rats

Autor: Beatriz Castañeda, Pilar Pizcueta, Sofía Pérez-del-Pulgar, Victoria Andreu, Jaime Bosch, Eduardo Moitinho, Juan-Carlos Bandi, Wilma Debernardi-Venon
Rok vydání: 2000
Předmět:
Zdroj: Hepatology. 31:581-586
ISSN: 0270-9139
DOI: 10.1002/hep.510310306
Popis: The aim of this study was to investigate the role of portal hypertension determining the severity of bleeding in portal hypertensive rats. The effects of section of branches of the ileocolic vein were studied in sham-operated (SO), partial portal vein-ligated (PPVL), and common bile duct-ligated (CBDL) rats. The ensuing hemorrhage was compared with that caused by section of femoral vein, where the portal hypertensive factor is excluded. In PPVL rats, section of branches of increasing size (divided into fourth, third, second, and first order) resulted in increasingly severe bleeding (arterial pressure: / +/- 4%, / 6 +/- 12%, / /15 +/- 8%, and / 28 +/- 13%; P
Databáze: OpenAIRE