| Autor: |
Yoshio Endou, Syouzou Sako, Masahiro Miura, Sachio Fushida, Keizou Taniguchi, Masumi Ichinose, Nobuyuki Takao, Haruaki Ishibashi, Akiyoshi Mizumoto, Satoshi Wakama, Yutaka Yonemura, Kazuo Nishihara, Shun-ichi Motoi, Yang Liu |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Pathology of Peritoneal Metastases ISBN: 9789811537721 |
| Popis: |
Mechanisms of peritoneal metastasis (PM) formation remain unclear. It has long been considered that the establishment of PM is a multi-step process. Here are the recent new concepts of the formation of PM, in terms of three patterns of PM: trans-mesothelial, trans-lymphatic, and superficial growing metastasis. Trans-mesothelial metastasis is established through detachment of cancer cells, adhesion on distant peritoneal surface, invasion into submesothelial tissue, and proliferation. Trans-lymphatic metastasis develops by the migration of peritoneal free cancer cells (PFCCs) into omental milky spots and/or initial lymphatic vessels. Superficial growing metastasis is established by growing of PFCCs on the peritoneal surface after trapping or adhesion to pocket-like structure or pouch in pelvic cavity or in peritoneum absorbed by negative pressure generated omental milky spots or initial lymphatic vessels. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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